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1

A randomized, double-blind, placebo-controlled clinical trial of the effectiveness of the novel serotonin type 3 receptor antagonist ramosetron in both male and female Japanese patients with diarrhea-predominant irritable bowel syndrome

Matsueda, Kei, Harasawa, Shigeru, Hongo, Michio, Hiwatashi, Nobuo, Sasaki, Daisuke

Journal:

Scandinavian Journal of Gastroenterology

Year:

2008

Language:

english

File:

PDF, 162 KB

english, 2008

2

Telomere shortening and the clinicopathologic characteristics of human colorectal carcinomas

Sho Takagi, Yoshitaka Kinouchi, Nobuo Hiwatashi, Masaki Chida, Fumio Nagashima, Seiichi Takahashi, Kenichi Negoro, Tooru Shimosegawa, Takayoshi Toyota

Journal:

Year:

1999

Language:

english

File:

PDF, 115 KB

english, 1999

3

Effect of weekend 5-aminosalicylic acid (mesalazine) enema as maintenance therapy for ulcerative colitis: Results from a randomized controlled study

Hiroshi Yokoyama, Sho Takagi, Shinichi Kuriyama, Shuichiro Takahashi, Hiroki Takahashi, Masahiro Iwabuchi, Seiichi Takahashi, Yoshitaka Kinouchi, Nobuo Hiwatashi, Ichiro Tsuji, Tooru Shimosegawa

Journal:

Inflammatory Bowel Diseases

Year:

2007

Language:

english

File:

PDF, 128 KB

english, 2007

4

Safety and efficacy of granulocyte and monocyte adsorption apheresis in patients with active ulcerative colitis: A multicenter study

Takashi Shimoyama, Koji Sawada, Nobuo Hiwatashi, Toshio Sawada, Kei Matsueda, Akihiro Munakata, Hitoshi Asakura, Takao Tanaka, Reiji Kasukawa, Ken Kimura, Yasuo Suzuki, Yukio Nagamachi, Tetsuichiro Mu

Journal:

Journal of Clinical Apheresis

Year:

2001

Language:

english

File:

PDF, 2.52 MB

english, 2001

5

Multiple depressed-type colonic cancer (IIC)-like configurations: metastases from gastric cancer

MASAHIRO IWABUCHI, NOBUO HIWATASHI, TATSUHIKO SUZUKI, SHIN TESHIMA, TOSHIHIRO SAITO, HIROYOSHI SUZUKI, YOSHIMASA MORI, JUNICHI ISHIBASHI, NOBUYUKI CHIDA, KEIICHI TADOKORO

Journal:

Digestive Endoscopy

Year:

2002

Language:

english

File:

PDF, 2.05 MB

english, 2002

6

Light and electron microscopic immunolocalization of endothelial leucocyte adhesion molecule-1 in inflammatory bowel disease

Haruo Ohtani, Shiro Nakamura, Yoshihisa Watanabe, Kouhei Fukushima, Takayuki Mizoi, Mitsuo Kimura, Nobuo Hiwatashi, Hiroshi Nagura

Journal:

Virchows Archiv

Year:

1992

Language:

english

File:

PDF, 2.81 MB

english, 1992

7

Relationship between glucocorticoid receptor and response to glucocorticoid therapy in ulcerative colitis

Takenobu Shimada, Nobuo Hiwatashi, Hideo Yamazaki, Yoshitaka Kinouchi, Takayoshi Toyota

Journal:

Diseases of the Colon & Rectum

Year:

1997

Language:

english

File:

PDF, 434 KB

english, 1997

8

Enteral nutrition for Crohn's disease in Japan

Nobuo Hiwatashi

Journal:

Diseases of the Colon & Rectum

Year:

1997

Language:

english

File:

PDF, 687 KB

english, 1997

9

Monitoring and antibacterial treatment for postoperative bacterial overgrowth in Crohn's disease

Yuji Funayama, Iwao Sasaki, Hiroo Naito, Kohei Fukushima, Chikashi Shibata, Tsuyoshi Masuko, Ken-ichi Takahashi, Hitoshi Ogawa, Shun Sato, Tatsuya Ueno, Mitsunori Noguchi, Nobuo Hiwatashi, Seiki Matsu

Journal:

Diseases of the Colon & Rectum

Year:

1999

Language:

english

File:

PDF, 612 KB

english, 1999

10

Analysis of thePTENgene mutation in polyposis syndromes and sporadic gastrointestinal tumors in Japanese patients

Kenichi Negoro, Seiichi Takahashi, Yoshitaka Kinouchi, Sho Takagi, Nobuo Hiwatashi, Ryo Ichinohasama, Tooru Shimosegawa, Takayoshi Toyota

Journal:

Diseases of the Colon & Rectum

Year:

2000

Language:

english

File:

PDF, 655 KB

english, 2000

11

Relationship between microsatellite instability and telomere shortening in colorectal cancer

Sho Takagi, Yoshitaka Kinouchi, Nobuo Hiwatashi, Fumio Nagashima, Masaki Chida, Seiichi Takahashi, Kenichi Negoro, Tooru Shimosegawa, Takayoshi Toyota

Journal:

Diseases of the Colon & Rectum

Year:

2000

Language:

english

File:

PDF, 638 KB

english, 2000

12

Crohn's disease in Japan

Tsuneyoshi Yao, Toshiyuki Matsui, Nobuo Hiwatashi

Journal:

Diseases of the Colon & Rectum

Year:

2000

Language:

english

File:

PDF, 1.24 MB

english, 2000

13

The role of interferonyin the pathogenesis of Crohn’s disease

Takashi Sasaki, Nobuo Hiwatashi, Hideo Yamazaki, Mitsunori Noguchi, Takayoshi Toyota

Journal:

Journal of Gastroenterology

Year:

1992

Language:

english

File:

PDF, 591 KB

english, 1992

14

Abstracts of selected papers presented at the 75th General Meeting of the Japanese Society of Gastroenterology March 27–29, 1989 — Yokohama, Japan

Akihiro Munakata, Tadashi Aisawa, Nobuo Hiwatashi, Mitsuo Kimura, Toshiyuki Matsui, Mitsuo Iida, Ken-ichi Yukawa, Shintaro Miyamoto, Tomoe Katsumata, Masahiro Igarashi, Kumiko Momma, Naoto Egawa, Kazu

Journal:

Journal of Gastroenterology

Year:

1990

Language:

english

File:

PDF, 1.07 MB

english, 1990

15

Clinical course and long-term prognosis of Japanese patients with ulcerative colitis

Nobuo Hiwatashi, Hideo Yamazaki, Mitsuo Kimura, Tomizou Morimoto, Hikaru Watanabe, Takayoshi Toyota

Journal:

Journal of Gastroenterology

Year:

1991

Language:

english

File:

PDF, 686 KB

english, 1991

16

Abstracts of selected papers presented at the 34th annual meeting of the japanese society of gastroenterology

Koji Nakamuta, Kazuya Makiyama, Masamichi Satomi, Makoto Yamamura, Nobuhide Oshitani, Atsuo Kitano, Nobuo Hiwatashi, Kaoru Ito, Etsuro Iwashita, Hiroshi Koyama, Akira Sugita, Tsuneo Fukushima, K. Suzu

Journal:

Journal of Gastroenterology

Year:

1993

Language:

english

File:

PDF, 1.87 MB

english, 1993

17

Clinical course and longterm prognosis of Japanese patients with Crohn’s disease: predictive factors, rates of operation, and mortality

Tatsuo Oriuchi, Nobuo Hiwatashi, Yoshitaka Kinouchi, Seiichi Takahashi, Sho Takagi, Kenichi Negoro, Tooru Shimosegawa

Journal:

Journal of Gastroenterology

Year:

2003

Language:

english

File:

PDF, 304 KB

english, 2003

18

Microsatellite instability and loss of heterozygosity in the nondysplastic colonic epithelium of ulcerative colitis

Seiichi Takahashi, Yasuhiro Kojima, Yoshitaka Kinouchi, Kenichi Negoro, Sho Takagi, Hiroyuki Aihara, Nobuya Obana, Keisuke Matsumoto, Nobuo Hiwatashi, Tooru Shimosegawa

Journal:

Journal of Gastroenterology

Year:

2003

Language:

english

File:

PDF, 199 KB

english, 2003

19

Acute pancreatitis complicating ulcerative colitis under administration of corticosteroid in surgical cases

Yuji Funayama, Kouhei Fukushima, Chikashi Shibata, Kaori Koyama, Koh Miura, Kenichi Takahashi, Akihiko Hashimoto, Iwao Sasaki, Yoshitaka Kinouchi, Nobuo Hiwatashi, Kazunori Takeda, Seiki Matsuno

Journal:

Journal of Gastroenterology

Year:

2004

Language:

english

File:

PDF, 188 KB

english, 2004

20

Development of consensus statements for the diagnosis and management of intestinal Behçet's disease using a modified Delphi approach

Kenji Kobayashi, Fumiaki Ueno, Seiji Bito, Yasushi Iwao, Tsuneo Fukushima, Nobuo Hiwatashi, Masahiro Igarashi, Bun-ei Iizuka, Takahide Matsuda, Toshiyuki Matsui, Takayuki Matsumoto, Akira Sugita, Mits

Journal:

Journal of Gastroenterology

Year:

2007

Language:

english

File:

PDF, 260 KB

english, 2007

21

Clinical trial: effects of an oral preparation of mesalazine at 4

Nobuo Hiwatashi, Yasuo Suzuki, Keiichi Mitsuyama, Akihiro Munakata, Toshifumi Hibi

Journal:

Journal of Gastroenterology

Year:

2011

Language:

english

File:

PDF, 264 KB

english, 2011

22

Telomere shortening in the colonic mucosa of patients with ulcerative colitis

Yoshitaka Kinouchi, Nobuo Hiwatashi, Masaki Chida, Fumio Nagashima, Sho Takagi, Hiroki Maekawa, Takayoshi Toyota

Journal:

Journal of Gastroenterology

Year:

1998

Language:

english

File:

PDF, 198 KB

english, 1998

23

Efficacy and Safety of Endoscopic Balloon Dilation for Crohn’s Strictures

Eiki Nomura, Sho Takagi, Tatsuya Kikuchi, Kenichi Negoro, Seiichi Takahashi, Yoshitaka Kinouchi, Nobuo Hiwatashi, Tooru Shimosegawa

Journal:

Diseases of the Colon & Rectum

Year:

2006

Language:

english

File:

PDF, 177 KB

english, 2006

24

An Evaluation of Mass Screening Using Fecal Occult Blood Test for Colorectal Cancer in Japan: A Case-Control Study

Nobuo Hiwatashi, Tomizo Morimoto, Akira Fukao, Hirofusa Sato, Nobuyuki Sugahara, Shigeru Hisamichi, Takayoshi Toyota

Journal:

Year:

1993

File:

PDF, 186 KB

1993

25

Three-dimensional Reconstruction and Fractal Geometric Analysis of Serrated Adenoma

Masahiro Iwabuchi, Mareyuki Endoh, Nobuo Hiwatashi, Yoshitaka Kinouchi, Tooru Shimosegawa, Takayuki Masuda, Takuya Moriya, Hironobu Sasano

Journal:

Year:

2002

Language:

english

File:

PDF, 25.72 MB

english, 2002

26

Leukocyte Removal Filter-Passed Lymphocytes Produce Large Amounts of Interleukin-4 in Immunotherapy for Inflammatory Bowel Disease: Role of Bystander Suppression

Mitsunori Noguchi, Nobuo Hiwatashi, Tomohiko Hayakawa, Takayoshi Toyota

Journal:

Therapeutic Apheresis and Dialysis

Year:

1998

Language:

english

File:

PDF, 533 KB

english, 1998

27

Psoas abscess complicating Crohn's disease: Report of two cases

Yuji Funayama, Iwao Sasaki, Hiroo Naito, Takashi Tsuchiya, Michinaga Takahashi, Kaori Koyama, Tsuyoshi Masuko, Ken-ichi Takahashi, Nobuo Hiwatashi, Seiki Matsuno

Journal:

Year:

1996

Language:

english

File:

PDF, 659 KB

english, 1996

28

Enhancement of human natural killer activity by the monoclonal Leu-11 antibodies

Shun-En Egawa, Toru Abo, Nobuo Hiwatashi

Journal:

Cellular Immunology

Year:

1987

Language:

english

File:

PDF, 1.01 MB

english, 1987

29

Changes in neuropeptide-containing nerves in human colonic mucosa with inflammatory bowel disease

Mitsuo Kimura, Takayuki Masuda, Nobuo Hiwatashi, Takayoshi Toyota, Hiroshi Nagura

Journal:

Pathology International

Year:

1994

Language:

english

File:

PDF, 1.03 MB

english, 1994

30

Relaxation of imprinting of the insulin-like growth factor II gene in colorectal cancer

Yoshitaka Kinouchi, Nobuo Hiwatashi, Seiichi Higashioka, Fumio Nagashima, Masaki Chida, Takayoshi Toyota

Journal:

Year:

1996

Language:

english

File:

PDF, 763 KB

english, 1996

31

The T3b gene promoter directs intestinal epithelial cell-specific expression in transgenic mice

Hiroyuki Aihara, Nobuo Hiwatashi, Shinji Kumagai, Yuhichi Obata, Tooru Shimosegawa, Takayoshi Toyota, Jun-ichi Miyazaki

Journal:

Year:

1999

Language:

english

File:

PDF, 341 KB

english, 1999

32

Crohn's disease is associated with novel polymorphisms in the 5'-flanking region of the tumor necrosis factor gene

Kenichi Negoro, Yoshitaka Kinouchi, Nobuo Hiwatashi, Seiichi Takahashi, Sho Takagi, Jo Satoh, Tooru Shimosegawa, Takayoshi Toyota

Journal:

Gastroenterology

Year:

1999

Language:

english

File:

PDF, 160 KB

english, 1999

33

Successful treatment of cap polyposis by avoidance of intraluminal trauma: clues to pathogenesis

Tatsuo Oriuchi, Yoshitaka Kinouchi, Mitsuo Kimura, Nobuo Hiwatashi, Tomohiko Hayakawa, Hiromitsu Watanabe, Shinji Yamada, Tetsuro Nishihira, Syuichi Ohtsuki, Takayoshi Toyota

Journal:

American Journal of Gastroenterology

Year:

2000

Language:

english

File:

PDF, 176 KB

english, 2000

34

Role of leukocyte apheresis in inflammatory bowel disease: Promotion of a Th2 cytokine-secreting profile

Mitsunori Noguchi, Nobuo Hiwatashi, Tadashi Ohara, Tooru Shimosegawa, Takayoshi Toyota

Journal:

Gastroenterology

Year:

2000

Language:

english

File:

PDF, 178 KB

english, 2000

35

S1066 Oral Alpha-4 Integrin Inhibitor (AJM300) in Patients with Active Crohn's Disease — A Randomized, Double-Blind, Placebo-Controlled Trial

Masakazu Takazoe, Mamoru Watanabe, Takaaki Kawaguchi, Takayuki Matsumoto, Nobuhide Oshitani, Nobuo Hiwatashi, Toshifumi Hibi

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 100 KB

english, 2009

36

Two Cases of Eosinophilic Gastroenteritis with Colonic Involvements and Rare Complications

Yoshitaka KINOUCHI, Nobuo HIWATASHI, Hideo YAMAZAKI, Naoaki TANNO, Yuji KUMAGAI, Takashi SASAKI, Hiroyuki HIRANO, Kaoru ITO, Itaru ENDOU, Hiroaki KAWARADA, Yoshiro KAYABA, Masaru KOIZUMI, Mitsuo KIMUR

Journal:

Digestive Endoscopy

Year:

1991

Language:

english

File:

PDF, 3.95 MB

english, 1991

37

Chronic Ischemic Colitis Associated with Marked Calcifications of the Mesenteric Vessels —Report of Two Cases—

Atsushi IKEHATA, Nobuo HIWATASHI, Hiroaki KAWARADA, Hideo YAMAZAKI, Kaoru ITO, Yoshitaka KINOUCHI, Mitsuo KIMURA, Mitsunori NOGUCHI, Hiroki MAEKAWA, Hiroto SUZUKI, Takenobu SHIMADA, Jun YAMAGATA, Taka

Journal:

Digestive Endoscopy

Year:

1994

Language:

english

File:

PDF, 964 KB

english, 1994

38

Crohn's Disease Consisting Solely of Aphthoid Ulcers at the Time of First Visit : —Clinical Features and Course—

Nobuo HIWATASHI, Hideo YAMAZAKI, Yoshitaka KINOUCHI, Kaoru ITO, Mitsuo KIMURA, Masayoshi KOBAYASHI, Masanori MITA, Takayoshi TOYOTA

Journal:

Digestive Endoscopy

Year:

1994

Language:

english

File:

PDF, 710 KB

english, 1994

39

High producer of lipoprotein(a) show a poor prognosis in patients with Crohn's disease

Noguchi, Mitsunori, Oikawa, Shinichi, Kinouchi, Yoshitaka, Hara, Susumu, Hiwatashi, Nobuo, Kumagai, Shinji, Shimosegawa, Tooru

Journal:

Gastroenterology

Year:

2003

Language:

english

File:

PDF, 170 KB

english, 2003

40

Electron paramagnetic resonance study of ferrous cytochrome P-450scc-nitric oxide complexes: effects of 20(R),22(R)-dihydroxycholesterol and reduced adrenodoxin

Tsubaki, Motonari, Hiwatashi, Atsuo, Ichikawa, Yoshiyuki, Fujimoto, Yoshinori, Ikekawa, Nobuo, Hori, Hiroshi

Journal:

Year:

1988

Language:

english

File:

PDF, 854 KB

english, 1988

41

Lack of association between IBD5 and Crohn's disease in Japanese patients demonstrates population-specific differences in inflammatory bowel disease

Tosa, Masaki, Negoro, Kenichi, Kinouchi, Yoshitaka, Abe, Hiroko, Nomura, Eiki, Takagi, Sho, Aihara, Hiroyuki, Oomori, Shinya, Sugimura, Mikako, Takahashi, Kazuma, Hiwatashi, Nobuo, Takahashi, Seiichi,

Journal:

Scandinavian Journal of Gastroenterology

Year:

2006

Language:

english

File:

PDF, 96 KB

english, 2006

42

Successful treatment of cap polyposis by avoidance of intraluminal trauma: clues to pathogenesis

Oriuchi, Tatsuo, Kinouchi, Yoshitaka, Kimura, Mitsuo, Hiwatashi, Nobuo, Hayakawa, Tomohiko, Watanabe, Hiromitsu, Yamada, Shinji, Nishihira, Tetsuro, Ohtsuki, Syuichi, Toyota, Takayoshi

Journal:

American Journal of Gastroenterology

Year:

2000

Language:

english

File:

PDF, 176 KB

english, 2000

43

Increased Secretion of Granulocyte-Macrophage Colony-Stimulating Factor in Mucosal Lesions of Inflammatory Bowel Disease

Noguchi, Mitsunori, Hiwatashi, Nobuo, Liu, Zhang-xu, Toyota, Takayoshi

Journal:

Year:

2001

Language:

english

File:

PDF, 258 KB

english, 2001

44

What Determines the Later Clinical Course of Patients Who Do Not Undergo Colectomy at the First Attack? A Japanese Cohort Study on Ulcerative Colitis

Shiga, Hisashi, Takagi, Sho, Inoue, Ryusuke, Kinouchi, Yoshitaka, Ohkubo, Takayoshi, Takahashi, Seiichi, Negoro, Kenichi, Yokoyama, Hiroshi, Kato, Seiichi, Fukushima, Kouhei, Hiwatashi, Nobuo, Shimose

Journal:

Year:

2010

Language:

english

File:

PDF, 191 KB

english, 2010

45

11β-Hydroxysteroid Dehydrogenase Type 2 and Mineralocorticoid Receptor in Human Fetal Development

Hirasawa, Gen, Sasano, Hironobu, Suzuki, Takashi, Takeyama, Junji, Muramatu, Yasunari, Fukushima, Kouhei, Hiwatashi, Nobuo, Toyota, Takayoshi, Nagura, Hiroshi, Krozowski, Zygmunt S.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

1999

File:

PDF, 604 KB

1999

46

Colocalization of 11β-Hydroxysteroid Dehydrogenase Type II and Mineralocorticoid Receptor in Human Epithelia

Hirasawa, Gen, Sasano, Hironobu, Takahashi, Ken-ichi, Fukushima, Kouhei, Suzuki, Takashi, Hiwatashi, Nobuo, Toyota, Takayosi, Krozowski, Zygmunt S., Nagura, Hiroshi

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

1997

Language:

english

File:

PDF, 1.18 MB

english, 1997

47

11β-Hydroxysteroid Dehydrogenase Type 2 and Mineralocorticoid Receptor in Human Fetal Development

Hirasawa, Gen, Sasano, Hironobu, Suzuki, Takashi, Takeyama, Junji, Muramatu, Yasunari, Fukushima, Kouhei, Hiwatashi, Nobuo, Toyota, Takayoshi, Nagura, Hiroshi, Krozowski, Zygmunt S.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

1999

Language:

english

File:

PDF, 604 KB

english, 1999

48

11β-Hydroxysteroid Dehydrogenase Type II and Mineralocorticoid Receptor in Human Placenta 1

Hirasawa, Gen, Takeyama, Junji, Sasano, Hironobu, Fukushima, Kouhei, Suzuki, Takashi, Muramatu, Yasunari, Darnel, Andrew D., Kaneko, Chika, Hiwatashi, Nobuo, Toyota, Takayoshi, Nagura, Hiroshi, Krozow

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2000

Language:

english

File:

PDF, 667 KB

english, 2000

49

New Vertebral Compression Fractures After Prophylactic Vertebroplasty in Osteoporotic Patients

Kamano, Hironori, Hiwatashi, Akio, Kobayashi, Nobuo, Fuwa, Sokun, Takahashi, Osamu, Saida, Yukihisa, Honda, Hiroshi, Numaguchi, Yuji

Journal:

American Journal of Roentgenology

Year:

2011

Language:

english

File:

PDF, 732 KB

english, 2011

50

Multicenter Randomized Controlled Trial for the Treatment of Ulcerative Colitis with a Leukocytapheresis Column

Sawada, Koji, Muto, Tetsuichiro, Shimoyama, Takashi, Satomi, Masamichi, Sawada, Toshio, Nagawa, Hirokazu, Hiwatashi, Nobuo, Asakura, Hitoshi, Hibi, Toshifumi

Journal:

Current Pharmaceutical Design

Year:

2003

Language:

english

File:

PDF, 162 KB

english, 2003